Screening and underwriting cases for life insurance involves sorting out lab tests. What do they mean? What are the normal values? What are the issues with abnormal values? Go to RiskTutor’s home page (http://www.risktutor.com) and click on Lab Test icon to connect to Lab Tests Online excellent resource information.
Using this resource with RiskTutor’s expertise will just put you even farther ahead in "winning" your next substandard case.


In a recent presentation to the Society for Neuroscience, Dr. Langleben from the University of Pennsylvania presented interesting information on using MRI imaging to "detect the truth." His research team had 18 people deliberately lie during a MRI.
When a person lied, activity in several regions of the brain increased. This may be the new forensic lie detector of the future!


British scientists report having taken the first major steps towards finding a way to vaccinate against CML (chronic myeloid leukemia). This is a very aggressive form of leukemia that affects mainly adults over 30.
Without a bone marrow transplant and chemotherapy, survival is normally less than five years.



Kidney Transplant Essentials | What are the indications for a kidney transplant?
What is the "source" for kidney transplants? | What happens after the kidney transplant?
Underwriting Discussion

Kidney Transplant Essentials

  • In 2000 there were 50,305 patients "waiting" for a kidney transplant
  • In 2000 there were 13,372 kidney transplant operations
  • Of the 13,372 kidney transplant operations in 2000, 5,293 were from living donors
  • The approximate "preservation time" for a kidney from a live donor is up to 72 hours
  • 94% of kidneys transplanted from a live donor are still functioning one year after surgery
  • 88% of kidneys transplanted from a non-living donor are still functioning one year after surgery

  • Irreversible (or approaching) end-stage kidney (renal) disease of any cause.


Remember: Healthy kidneys do three things:

1. Remove wastes from the blood
2. Regulate levels of water and different minerals
3. Produce hormones that control body functions

When the kidneys no longer work well enough, dialysis treatment or a kidney transplant is required.

There are two sources for kidney transplants: a "living donor" transplant and a "cadaveric" transplant.

Living donor transplants are usually from a blood relative (i.e. immediate family members). The donor’s blood group and tissue type must "match" the person receiving the kidney.

Cadaveric donor transplants are from a person who has recently died. This issue of "compatibility" is still key to "matching" a kidney between the deceased and a potential recipient.


Following the kidney transplant, it is important to monitor both the function of the kidney and prevent "rejection" by the body. To do this requires blood tests and medications.

Blood tests that are used in the post-surgical period include:

  • WBC (white blood cells)
  • HCT (hematocrit or % of red blood cells in the blood)
  • PLT (platelets)
  • BUN (a waste product normally removed by the kidney)
  • Creatinine (a waste product normally removed by the kidney)
  • Electrolytes

Below is a typical list of medications that are used in the post-surgical period include:

  • Cellcept—Fights rejection by decreasing the number of white cells the immune system produces
  • Sandimmume—Suppresses the immune system to ward off rejection
  • Prograf—Suppresses the immune system to ward off rejection
  • Deltasone or prednisone—Prevents and treats rejection
  • Imuran—Suppress the immune system to ward off rejection
  • Orthoclone—Suppresses the immune system to ward off rejection
  • Zenzpax—First genetically engineered medication used to ward off rejection

A client with a history of a kidney transplant presents underwriting problems. Survival following a kidney transplant depends on five things:

  • Age
  • What caused the kidney failure
  • Severity of associated disorders
  • Closeness of match
  • Type of donor (live or cadaver)

These are the primary factors that are assessed in determining insurability. The following questions will allow you to screen clients with a history of kidney transplant.

1) What was the cause of the kidney failure that led to transplantation?

Underwriting Comment:
It is important to know what precipitated the kidney failure. Was it a disease of the kidney (i.e. glomerulonephritis), or was it secondary to another medical problem (i.e. diabetes)? The cause (also called etiology) will have a significant bearing on the both the success of the transplant and the assessment for life insurance.

2) How old was the client at the time of the kidney transplant?

Underwriting Comment:
The ideal age for a kidney transplant is between 15 and 65. Clients under 15 or over 65 are considered for life insurance on an "individual consideration basis."

3) What was the source of the new kidney?

Underwriting Comment:
The ideal source is a kidney from an identical twin. After that, a kidney from a live, related donor who has an identical "match" is the next best choice. This is usually from a sibling. The next best choice is from a live donor who had a good "match". Finally, there is a kidney from a cadaver.

REMEMBER: The time of postponement from the date of the kidney transplant until the client is insurable depends first and foremost on the source of the kidney (i.e. 3 months for an identical twin as opposed to 2 years with a cadaveric kidney). In addition, the cost of insurance for the client increases with a less than optimal "replacement" kidney.

4) What are the current medications that the client is taking?

Underwriting Comment:
As noted above, transplantation requires the use of medications in the post-surgical period. It is important to document all the medications the client is taking for their kidney transplant and any other medical problems (i.e. hypertension or diabetes).

5) Does the client have other medical problems?

Underwriting Comment:
Clients with additional significant medical problems in addition to their kidney transplant will generally not be insurable for individual coverage. It is important to "discover" the full extent of their medical history in the "screening" phase of the case.

Featured Topic for December 2001 Newsletter

Alcohol Abuse
Underwriting Essentials

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